DMRG member Dr Tineke van de Weijer is the first author of a review published in the Journal of Applied Physiology, 'Mini-Review on Cardiac Metabolic Imaging: current imaging modalities and future perspectives'. The review discusses a range of non-invasive imaging techniques allowing a detailed investigation of cardiac metabolism in health and disease, including Magnetic Resonance Spectroscopy (MRS) techniques for determination of metabolite content (triglycerides, glucose, ATP, phosphocreatine ...
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Author: Joris Hoeks
24 May 2017: thesis defence ‘Myocellular lipid droplets and insulin sensitivity: A microscopy approach’
PhD student Anne Gemmink will defend her thesis, 'Myocellular lipid droplets and insulin sensitivity: A microscopy approach' on 24 May. Read more here.
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Magnetic Resonance in Medicine publishes spectral editing paper
Magnetic Resonance in Medicine published a DMRG article titled 'Measurement of Lipid Composition in Human Skeletal Muscle and Adipose Tissue With 1H-MRS Homonuclear Spectral Editing'. The study demonstrates the feasibility of spectral editing techniques for ectopic lipid store characterization with 1H-MRS, regardless of spectral resolution, offering the opportunity to study ectopic lipid composition in relation to metabolic diseases.
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Resveratrol study published in Diabetes Care
Diabetes Care published a DMRG study titled 'Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial.' The study sought to determine whether resveratrol supplementation can improve insulin sensitivity and promote overall metabolic health on top of standard diabetes care. Results suggest that resveratrol supplementation does not improve hepatic or peripheral insulin sensitivity, and emphasize the need to perform studies in drug-naive patients...
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Benefit BBQ for Diabetes Foundation
Already for the fourth time in a row DMRG will participate in the DiaBeatIt Run: a double marathon from Rotterdam to Amsterdam, including the 589 stair steps of the 'Euromast', to raise money for the Dutch Diabetes Foundation. Each year we try to raise more money than the year before and to this extent we organize al kinds of activities such as a movie night, baking cakes and a sports day for children. This year one of our big events is an end-of-summer benefit BBQ sponsored by the departments o...
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Day-night rhythm study published in Molecular Metabolism
Molecular Metabolism recently published DMRG's latest study entitled "Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity". A disturbed day-night rhythm is associated with metabolic perturbations that can lead to obesity and type 2 diabetes mellitus (T2DM). In skeletal muscle, a reduced oxidative capacity is also associated with the development of T2DM. The results of this new study suggest that the biological clock drives robust rhythms in human skeletal muscle oxida...
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Prestigious Minkowski Prize awarded to Patrick Schrauwen
For his translational research on skeletal muscle insulin resistance, mitochondrial function and energy metabolism in the pathogenesis of type 2 diabetes Patrick Schrauwen has been awarded this year’s Minkowski Prize of the European Association for the Study of Diabetes (EASD). It is considered the most important European diabetes research award for young scientists and is endowed with 20,000 euros. Since the first award in 1966, Schrauwen is only the second dutch scientist to win this prestigio...
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New DMRG publications!
DMRG recently published three new papers. These papers can be found via the links below.
Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J. ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia, in press, 2016.
Lindeboom L, Bruls YM, van Ewijk PA, Hesselink MK, Wildberger JE, Schrauwen P, Schrauwen-Hinderling VB. Longitudinal relaxation time edi...
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Best Abstract Award for Dirk van Moorsel
For his research entitled “Demonstration of a Day-Night Rhythm in Skeletal Muscle Mitochondrial Function”, Dirk van Moorsel received the award for best abstract translational endocrinology, during the annual Dutch Endocrine Meeting on January 30th, 2016. For the award; the independent jury scored the quality of the abstract, the presentation and the way of handling questions.
The research was a collaboration between the division of endocrinology of the Maastricht University Medical Center (B....
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New DMRG PhD students!
DMRG has welcomed 3 new PhD students in the past months:
Eva Fechner, started in September 2015. Her project will focus on the influence of dietary interventions on metabolic flexibility.
Carlijn Remie, started in October 2015. Carlijn's first study will focus on the effects of 10 day cold acclimation on insulin sensitivity and cardiovascular risk parameters in type 2 diabetic patients.
Kay Roumans, started in January 2016. Kay will first work in the group of Wouter van Marken Lichtenbel...
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