During the virtual EASD meeting, Yvonne Bruls presented her work on carnitine supplementation in type 2 diabetes patients. The key messages of this presentation were that: Three months carnitine supplementation (2970 mg/day) increased plasma free carnitine availability in type 2 diabetes patients Carnitine supplementation increased resting skeletal muscle acetylcarnitine concentrations and...

Published in Diabetologia online ahead of print is the article of Sabine Daemen and colleagues titled: "Label-free CARS microscopy reveals similar triacylglycerol acyl chain length and saturation in myocellular lipid droplets of athletes and individuals with type 2 diabetes". The full article can be found online: https://doi.org/10.1007/s00125-020-05266-6 Read the abstract below: AIMS/HY...

This recent article of our colleague Emmani titled "Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers" is now online available. This article is published in BMC Medical Genomics and the full article can be found here:  https://doi.org/10.1186/s12920-020-00784-z  Read the abstract below: PURPOSE: Cold acclimation ...

Pandi, together with Kim Brouwers, Joachim Wildberger, Vera Schrauwen-Hinderling, and Lucas Lindeboom, published a new article on the 3rd of July on a new MR sequence for 13C-tracking experiments in human liver in Vivo titled: " ". This article is published in Magnetic Resonance in Medicine and the full article can be found here: https://doi.org/10.1002/mrm.28394 Read the abstract below: PUR...

Yes! We are starting up again with our clinical studies. Many projects came to a sudden halt because of all precaution measures regarding COVID-19. Although the start-up is slow, we are happy to be able to get back to our research unit and welcome participants again. Good luck to all our colleagues with getting back into the rhythm of screenings and test days!

A manuscript of Alex Houzelle, former DMRG member and written together with some of the DMRG colleagues, is now online: "MicroRNA‐204‐5p modulates mitochondrial biogenesis in C2C12 myotubes and associates with oxidative capacity in humans". Published in Journal of Cellular Biology, the full article can be accessed with the following link: https://doi.org/10.1002/jcp.29797 Read the abstract ...

A new article of our department with first author Marlies de Ligt is online now: "No effect of resveratrol supplementation after 6 months on insulin sensitivity in overweight adults: a randomized trial". This article is published in The American Journal of Clinical Nutrition and can be found on https://doi.org/10.1093/ajcn/nqaa125. Read the abstract below: BACKGROUND: Effects of resveratrol ...

Good news! We finally are able to start up the lab work again at our department! A bit lonely still with most of our colleagues still working from home, but happy to be able to start analyzing. Hopefully, we will soon be able to join our colleagues at Maastricht University. 

Our colleague Matthijs Hesselink collaborated on a paper titled: "Lipid droplets accumulate in the hypothalamus of mice and humans with and without metabolic disease", published in Neuroendocrinology. The full article can be found on https://doi.org/10.1159/000508735 Read the abstract below: BACKGROUND: In peripheral tissues, the lipid droplet (LD) organelle links lipid metabolism, inflammat...

Although we are getting used to working from home, we still miss our colleagues: celebrating birthdays, having a chat at the coffee machine, or walking by somebody's office for a quick question. To keep each other updated and have an informal moment for interaction, we have biweekly meetings during which 2 colleagues talk about what they have been up to the last couple of weeks, work-related or pe...