The thesis defence of Niels Connell can be followed via the following link: https://youtu.be/joKhwHaE7BE

The newest review by Charlotte Andriessen has been published (ahead of print) in the International Journal of Obesity with the title: "The importance of 24-h metabolism in obesity-related metabolic disorders: opportunities for timed interventions". The  review can be found online: https://doi.org/10.1038/s41366-020-00719-9 Read the abstract below: Various metabolic processes in the body osci...

Last week, a new article of Kay Roumans was published online ahead of print: "Liver fat storage pathways: methodologies and dietary effects". The article in Current Opinion in Lipodology can be found here: https://doi.org/10.1097/mol.0000000000000720  Read the abstract below: PURPOSE OF REVIEW: Nonalcoholic fatty liver is the result of an imbalance between lipid storage [from meal, de novo l...

Our colleague Anne Gemmink, together with other members of our research group, published an article titled: "Decoration of myocellular lipid droplets with perilipins as a marker for in vivo lipid droplet dynamics: A super-resolution microscopy study in trained athletes and insulin resistant individuals". This article is published in Biochimica et Biophysica Acta - Molecular and Cell Biology of Lip...

The very first article of Froukje Vanweert as first author has been published titled "Elevated plasma branched-chain amino acid levels correlate with type 2 diabetes-related metabolic disturbances". The full article can be found online: https://doi.org/10.1210/clinem/dgaa751 Read the abstract below: CONTEXT: Patients with type 2 diabetes (T2DM) have elevated plasma branched-chain amino acid ...

Last week during the virtual EASD meeting, Yvo op den Kamp presented his work on the effects of 5 weeks of treatment with dapagliflozin, a SGLT2 inhibitor, on energy metabolism in patients with type 2 diabetes. The key messages of this presentation were that dapagliflozin treatment vs placebo resulted in: Unchanged 24-h energy expenditure, while 24-h fatty acid oxidation increased, inducing a...

Now online available is the most recent article by Yvonne Bruls and colleagues titled " L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility". The full article can be found online: https://doi.org/10.1371/journal.pone.0239506 Read the abstract below: BACKGROUND: Low carnitine status may underlie the development of insulin resistance and metabol...

During the virtual EASD meeting, Yvonne Bruls presented her work on carnitine supplementation in type 2 diabetes patients. The key messages of this presentation were that: Three months carnitine supplementation (2970 mg/day) increased plasma free carnitine availability in type 2 diabetes patients Carnitine supplementation increased resting skeletal muscle acetylcarnitine concentrations and...

Published in Diabetologia online ahead of print is the article of Sabine Daemen and colleagues titled: "Label-free CARS microscopy reveals similar triacylglycerol acyl chain length and saturation in myocellular lipid droplets of athletes and individuals with type 2 diabetes". The full article can be found online: https://doi.org/10.1007/s00125-020-05266-6 Read the abstract below: AIMS/HY...

This recent article of our colleague Emmani titled "Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers" is now online available. This article is published in BMC Medical Genomics and the full article can be found here:  https://doi.org/10.1186/s12920-020-00784-z  Read the abstract below: PURPOSE: Cold acclimation ...