Publication on DAPAMAAST trail

Publication on DAPAMAAST trail
Published in Diabetes Care by our colleague Yvo op den Kamp and now available online ahead of print is the article called: "Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial". Full article can be found here: https://doi.org/10.2337/dc20-2887 Read the abstract below. OBJECTIVE: SGTL2 inhibitors inc...
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Long-term research on the effects of lifestyle on the biological clock

Long-term research on the effects of lifestyle on the biological clock
Scientists from the Netherlands and Canada are to investigate whether lifestyle changes can help to restore the 24-hour rhythm of people at a high risk of developing type 2 diabetes. The Dutch researchers, including Professor Patrick Schrauwen of Maastricht University, have already concluded that people with a predisposition to type 2 diabetes have a disrupted circadian rhythm, or biological cl...
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Publication in Nature Communication by our team members

Publication in Nature Communication by our team members
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A recent manuscript published in Nature Communication by our team show that mild cold acclimation for 10 days in patients with type 2 diabetes in which observable, overt shivering was prevented, does not result in improved insulin sensitivity. The full article can be found here: https://doi.org/10.1038/s41467-021-21813-0 ABSTRACT Mild cold acclimation for 10 days has been previously shown to...
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Publication by Sten van Beek in the American Journal of Physiology Metabolism & Endocrinology

Publication by Sten van Beek in the American Journal of Physiology Metabolism & Endocrinology
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An interesting read by our colleague Sten van Beek on "Prolonged β 2-adrenergic agonist treatment improves glucose homeostasis in diet-induced obese UCP1 -/- mice". This manuscript is published in the American Journal of Physiology Metabolism & Endocrinology and full text can be found online: https://doi.org/10.1152/ajpendo.00324.2020  Read the abstract below: Prolonged supplementation...
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Review published ahead of print by Charlotte Andriessen

Review published ahead of print by Charlotte Andriessen
The newest review by Charlotte Andriessen has been published (ahead of print) in the International Journal of Obesity with the title: "The importance of 24-h metabolism in obesity-related metabolic disorders: opportunities for timed interventions". The  review can be found online: https://doi.org/10.1038/s41366-020-00719-9 Read the abstract below: Various metabolic processes in the body osci...
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New review by Kay Roumans

New review by Kay Roumans
Last week, a new article of Kay Roumans was published online ahead of print: "Liver fat storage pathways: methodologies and dietary effects". The article in Current Opinion in Lipodology can be found here: https://doi.org/10.1097/mol.0000000000000720  Read the abstract below: PURPOSE OF REVIEW: Nonalcoholic fatty liver is the result of an imbalance between lipid storage [from meal, de novo l...
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Article by Anne Gemmink

Article by Anne Gemmink
Our colleague Anne Gemmink, together with other members of our research group, published an article titled: "Decoration of myocellular lipid droplets with perilipins as a marker for in vivo lipid droplet dynamics: A super-resolution microscopy study in trained athletes and insulin resistant individuals". This article is published in Biochimica et Biophysica Acta - Molecular and Cell Biology of Lip...
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New article by Froukje Vanweert

New article by Froukje Vanweert
The very first article of Froukje Vanweert as first author has been published titled "Elevated plasma branched-chain amino acid levels correlate with type 2 diabetes-related metabolic disturbances". The full article can be found online: https://doi.org/10.1210/clinem/dgaa751 Read the abstract below: CONTEXT: Patients with type 2 diabetes (T2DM) have elevated plasma branched-chain amino acid ...
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EASD – Presentation by Yvo op den Kamp

EASD – Presentation by Yvo op den Kamp
Last week during the virtual EASD meeting, Yvo op den Kamp presented his work on the effects of 5 weeks of treatment with dapagliflozin, a SGLT2 inhibitor, on energy metabolism in patients with type 2 diabetes. The key messages of this presentation were that dapagliflozin treatment vs placebo resulted in: Unchanged 24-h energy expenditure, while 24-h fatty acid oxidation increased, inducing a...
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