The article from our colleague Sten van Beek is now online available and will be published in Nature Communications with the following title: “Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial”. The full article can be found here: https://doi.org/10.1038/s41467-023-35798-5 Read the abstract below. Abst...

The article from our colleague Anna Veelen is now online available and will be published in Metabolism with the following title: “Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial”. The full article can be found here: https://doi.org/10.1016/j.metabol.2022.155396...

The article from our colleague Jan-Frieder Harmsen is now online available and will be published in Cell Reports with the following title: “Divergent remodeling of the skeletal muscle metabolome over 24 h between young, healthy men and older, metabolically compromised men”. The full article can be found here: https://doi.org/10.1016/j.celrep.2022.111786 Read the abstract below. ...

Our colleague Froukje Vanweert has been awarded a Kootstra Talent Fellowship. Froukje will focus on the role of branched-chain amino acid (BCAA)  catabolism in type 2 diabetes. The role of BCAA, a specific group of essential amino acids, in the development of insulin resistance and type 2 diabetes has been a topic of renewed interest. Patients with type 2 diabetes feature elevated BCAA levels in p...

The article from our colleague Rodrigo Mancilla is now online available and will be published in  JCI Insight with the following title: “Skeletal muscle mitochondrial inertia associates with carnitine acetyltransferase activity and physical function in humans”. The full article can be found here: https://doi.org/10.1172/jci.insight.163855 Read the abstract below. Background: At the on...

Sten van Beek successfully defended his thesis today, 23rd of November 2022, at 4:00 p.m.. His thesis is called "Mechanisms of cold-induced improvements in glucose homeostasis".

The article from our colleagues Anne Gemmink and Yvo op den Kamp is now online available and will be published in  Molecular metabolism with the following title: “Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism”. The full article can be found here: https://doi.org/10.1016/j.molmet.2022.101620   Read the abstract below. ...

The review from our colleague Froukje Vanweert is now online available and will be published in  Nutrition & Diabetes with the following title: “Role of brached-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCCA metabolism in type 2 diabetes”. The full article can be found here: https://doi.org/10.1038/s41387-022-00213-3 &nb...

The article from our colleague Charlotte Andriessen is now online available and will be published in  Diabetologia with the following title: “Three weeks of time-restricted eating improves glucose homeostasis in adults with type 2 diabetes but does not improve insulin sensitivity: a randomised crossover trial”. The full article can be found here: https://doi.org/10.1007/s00125-022-05752-z &n...

The article from our colleague Evi Koene is now online available and will be published in Current opinion in clinical nutrition and metabolic care with the following title: “Novel insights in intestinal and hepatic fructose metabolism: from mice to men". The full article can be found here: https://doi.org/10.3390/biom11111680 Read the abstract below: Purpose of review: The rise in fruct...