Kay published a new article titled "Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance" in Nature Communications. The full article can be found on https://doi.org/10.1038/s41467-020-15684-0  Read the abstract below: Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Hepatic saturated fatty acids (SFA) may be a marker...

Carlijn published a new article titled "Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans" in The American Journal of Clinical Nutrition. The full article can be found on: https://doi.org/10.1093/ajcn/nqaa072  Read the abstract below: BACKGROUND: Nicotinamide riboside (NR) is an NAD+ precursor that boosts cellular NAD+ concentrations. Preclinical studies have shown profound metabolic health effects after...

It is nice to see our colleagues, even if it is digital! After working from home for 5 weeks we had a group meeting to share the latest news, something we used to do on a weekly basis in person. Hope to see you all soon! 

How to celebrate your birthday with your colleagues while working from home? Easy: a digital pub quiz! A small remark is that everybody had to bring their own drinks and snack. Congratulations to Patrick Schrauwen with organizing a successful pub quiz and of course with your birthday.

Yvonne Bruls published her article titled "Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial." in EBioMedicine. The full article can be found on https://doi.org/10.1016/j.ebiom.2019.10.017 Read the abstract below. BACKGROUND: Type 2 diabetes patients and individuals at risk of developing diabetes are characterized by metabolic inflexibility and disturbed glucose...

To have healthy employees, Maastricht UMC has organized the Healthy Living Week for all employees. On Wednesday, our colleague Kay Roumans was able to explain to people with an exiting quiz that simple changes in your lifestyle or eating habits can also be very healthy, for example exposing yourself to a colder temperature. 

Recently, Lotte Grevendonk was a co-author in the article titled "Older adults demonstrate interlimb transfer of reactive gait adaptations to repeated unpredictable gait perturbations.", published in Geroscience. The full article can be found on https://doi.org/10.1101/673574  Read the abstract below. The ability to rapidly adjust gait to cope with unexpected mechanical perturbations declines with ageing. Previous studies however, have not ensured that pre-perturbation gait stability was e...

Esther Phielix has published a new article titled "Athletes feature greater rates of muscle glucose transport and glycogen synthesis during lipid infusion" in the Journal of Clinical Investigation Insight. The full article can be found on https://doi.org/10.1172/jci.insight.127928  Read the abstract below. BACKGROUND: Insulin resistance results from impaired skeletal muscle glucose transport/phosphorylation, linked to augmented lipid availability. Despite greater intramuscular lipids, athlet...

The Diabetes and Metabolism Research Group spent some time outside of the research labs to fully align with the circadian rhythm in the form of a treasure hunt on and around the Sint Pietersberg and open-air winter barbecue.