The article from our former colleague Edmundo Erazo-Tapia is now online available in Nature Metabolism with the following title: "Cotadutide promotes glycogenolysis in people with overweight or obesity diagnosed with type 2 diabetes”.
The full article can be found here: https://doi.org/10.1038/s42255-023-00938-0
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Abstract
Cotadutide is a dual glucagon-like peptide 1 and glucagon receptor agonist under development for the treatment of non-alcoholic steatohepatitis and ...
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Author: Joris Hoeks
New review online on the advances and challenges in measuring hepatic glucose uptake with FDG PET
The review from our colleague Jeremy Basset is now online available and will be published in Diabetologia with the following title: "Advances and challenges in measuring hepatic glucose uptake with FDG PET: implications for diabetes research”.
The full article can be found here: https://doi.org/10.1007/s00125-023-06055-7
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Abstract
The liver plays a crucial role in the control of glucose homeostasis and is therefore of great interest in the investigation of the develop...
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New article on the effects of exercise training on the clock
The article from our former colleague Jan-Frieder Harmsen is now online available and in The Journal of Physiology with the following title: "Exercise training modifies skeletal muscle clock gene expression but not 24-hour rhythmicity in substrate metabolism of men with insulin resistance”.
The full article can be found here: https://doi.org/10.1113/JP285523
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Abstract
Twenty-four hour rhythmicity in whole-body substrate metabolism, skeletal muscle clock gene expr...
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New article online on the impact of prolonged fasting on 24h energy metabolism
The article from our former colleague Charlotte Andriessen is now online available and will be published in Clinical Nutrition with the following title: "The impact of prolonged fasting on 24h energy metabolism and its 24h rhythmicity in healthy, lean males: A randomized cross-over trial”.
The full article can be found here: https://doi.org/10.1016/j.clnu.2023.10.010
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Abstract
Objective: Human energy expenditure and substrate oxidation are under circadian control an...
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New review on ectopic lipid deposition in muscle and liver is now online
The article from our former colleague Vera de Wit is now online available and will be published in Obesity with the following title: "The tissue-specific metabolic effects of the PPARα agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study”.
The full article can be found here: https://doi.org/10.1002/oby.23874
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Abstract
Advances in the development of noninvasive imaging techniques have spurred in...
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New publication on the tissue-specific metabolic effects of the PPARα agonist ciprofibrate
The article from our former colleague Vera de Wit is now online available and will be published in Obesity with the following title: "The tissue-specific metabolic effects of the PPARα agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study”.
The full article can be found here: https://doi.org/10.1002/oby.23874
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Abstract
Objective: Insulin resistance is characterized by ectopic fat accumulation le...
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New article on markers of skeletal muscle mitochondrial function
The article from our former colleague Rodrigo Mancilla now online available and will be published in Physiological Reports with the following title: "Invasive and noninvasive markers of human skeletal muscle mitochondrial function”.
The full article can be found here: https://doi.org/10.14814/phy2.15734
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Abstract
Mitochondria are organelles that fuel cellular energy requirements by ATP formation via aerobic metabolism. Given the wide variety of methods to assess ske...
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New publication on PCr/ATP ratios and mitochondrial function in the heart
The article from our former colleague Vera de Wit is now online available and will be published in Scientific Reports with the following title: PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans”.
The full article can be found here: https://doi.org/10.1038/s41598-023-35041-7
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Abstract
Cardiac energy status, measured as phosphocreatine (PCr)/adenosine triphosphate (ATP) ratio with 31P-Magnetic Resonance Spectroscopy (31P-M...
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New article on twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration
The article from our colleague Anne Gemmink is now online available and will be published in Molecular metabolism with the following title: “Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity”.
The full article can be found here: https://doi.org/10.1016/j.molmet.2023.101727
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Abstract
Mitochondrial network dynamics may play role i...
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New article on replacing foods with a High-Glycemic Index and High in Saturated Fat by Alternatives with a Low Glycemic Index and Low Saturated Fat Reduces Hepatic Fat
The article from our colleagues Jeremy Basset-Sagarminaga and Kay Roumans isnow online available and will be published in Nutrients withthe following title: “Replacing Foods with a High-Glycemic Index and High inSaturated Fat by Alternatives with a Low Glycemic Index and Low Saturated FatReduces Hepatic Fat, Even in Isocaloric and Macronutrient Matched Conditions”.
The full article can be found here: https://doi.org/10.3390/nu15030735
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Abstract
Backgrou...
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