2011

Wijers SL, Schrauwen P, van Baak MA, Saris WH, van Marken Lichtenbelt WD: Beta-adrenergic receptor blockade does not inhibit cold-induced thermogenesis in humans: possible involvement of brown adipose tissue. Journal of Clinical Endocrinology and Metabolism, 96, E598-605, 2011.

Vijgen GH, Bouvy ND, Teule GJ, Brans B, Schrauwen P, van Marken Lichtenbelt WD: Brown adipose tissue in morbidly obese subjects. PloS one, 6, e17247, 2011.

van Schothorst EM, Bunschoten A, Verlinde E, Schrauwen P, Keijer J: Glycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue. Physiological genomics, 43, 942-949, 2011.

van Marken Lichtenbelt WD, Schrauwen P: Implications of nonshivering thermogenesis for energy balance regulation in humans. American Journal of Physiology – Regulatory, integrative and comparative physiology, 301, R285-296, 2011.

van Herpen NA, Schrauwen-Hinderling VB, Schaart G, Mensink RP, Schrauwen P: Three weeks on a high-fat diet increases intrahepatic lipid accumulation and decreases metabolic flexibility in healthy overweight men. Journal of Clinical Endocrinology and Metabolism, 96, E691-695, 2011.

van den Berg SA, van Marken Lichtenbelt W, Willems van Dijk K, Schrauwen P: Skeletal muscle mitochondrial uncoupling, adaptive thermogenesis and energy expenditure. Current Opinion in Clinical Nutrition and Metabolic Care, 14, 243-249, 2011.

van de Weijer T, Schrauwen-Hinderling VB, Schrauwen P: Lipotoxicity in type 2 diabetic cardiomyopathy. Cardiovascular Research, 92, 10-18, 2011.

Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P: Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metabolism, 14, 612-622, 2011.

Timmers S, de Vogel-van den Bosch J, Hesselink MK, van Beurden D, Schaart G, Ferraz MJ, Losen M, Martinez-Martinez P, De Baets MH, Aerts JM, Schrauwen P: Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle. PloS one, 6, e14503, 2011.

Timmers S, de Vogel-van den Bosch J, de Wit N, Schaart G, van Beurden D, Hesselink M, van der Meer R, Schrauwen P: Differential effects of saturated versus unsaturated dietary fatty acids on weight gain and myocellular lipid profiles in mice. Nutrition & Diabetes, 1, e11, 2011.

Schrauwen-Hinderling VB, Meex RC, Hesselink MK, van de Weijer T, Leiner T, Schar M, Lamb HJ, Wildberger JE, Glatz JF, Schrauwen P, Kooi ME: Cardiac lipid content is unresponsive to a physical activity training intervention in type 2 diabetic patients, despite improved ejection fraction. Cardiovascular Diabetology, 10, 47, 2011.

Nabben M, Shabalina IG, Moonen-Kornips E, van Beurden D, Cannon B, Schrauwen P, Nedergaard J, Hoeks J: Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice. Biochimica et Biophysica Acta, 1807, 1095-1105, 2011.

Nabben M, Hoeks J, Moonen-Kornips E, van Beurden D, Briede JJ, Hesselink MK, Glatz JF, Schrauwen P: Significance of uncoupling protein 3 in mitochondrial function upon mid- and long-term dietary high-fat exposure. FEBS letters, 585, 4010-4017, 2011.

Meex RC, Phielix E, Moonen-Kornips E, Schrauwen P, Hesselink MK: Stimulation of human whole-body energy expenditure by salsalate is fueled by higher lipid oxidation under fasting conditions and by higher oxidative glucose disposal under insulin-stimulated conditions. Journal of Clinical Endocrinology and Metabolism, 96, 1415-1423, 2011.

Jans A, Sparks LM, van Hees AM, Gjelstad IM, Tierney AC, Riserus U, Drevon CA, Roche HM, Schrauwen P, Blaak EE: Transcriptional metabolic inflexibility in skeletal muscle among individuals with increasing insulin resistance. Obesity, 19, 2158-2166, 2011.

Hesselink MK, Schrauwen P: Diet or diet plus physical activity in patients with early type 2 diabetes. Lancet, 378, 2066-2067, 2011.

Haemmerle G, Moustafa T, Woelkart G, Buttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rulicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R: ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nature Medicine, 17, 1076-1085, 2011.

Glatz JF, de Groot RH, Hesselink MK, Schrauwen P: Lipids in metabolic health and disease. Prostaglandins, leukotrienes, and essential fatty acids, 85, 195, 2011.

De Vogel-van den Bosch J, van den Berg SA, Bijland S, Voshol PJ, Havekes LM, Romijn HA, Hoeks J, van Beurden D, Hesselink MK, Schrauwen P, van Dijk KW: High-fat diets rich in medium- versus long-chain fatty acids induce distinct patterns of tissue specific insulin resistance. Journal of Nutritional Biochemistry, 22, 366-371, 2011.

De Vogel-van den Bosch J, Hoeks J, Timmers S, Houten SM, van Dijk PJ, Boon W, Van Beurden D, Schaart G, Kersten S, Voshol PJ, Wanders RJ, Hesselink MK, Schrauwen P: The effects of long- or medium-chain fat diets on glucose tolerance and myocellular content of lipid intermediates in rats. Obesity, 19, 792-799, 2011.

Brouwers O, Niessen PM, Ferreira I, Miyata T, Scheffer PG, Teerlink T, Schrauwen P, Brownlee M, Stehouwer CD, Schalkwijk CG: Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats. The Journal of Biological Chemistry, 286, 1374-1380, 2011.

Brands M, Hoeks J, Sauerwein HP, Ackermans MT, Ouwens M, Lammers NM, van der Plas MN, Schrauwen P, Groen AK, Serlie MJ: Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men. Metabolism: clinical and experimental, 60, 1398-1405, 2011.

Bilet L, van de Weijer T, Hesselink MK, Glatz JF, Lamb HJ, Wildberger J, Kooi ME, Schrauwen P, Schrauwen-Hinderling VB: Exercise-induced modulation of cardiac lipid content in healthy lean young men. Basic research in cardiology, 106, 307-315, 2011.