DMRG in Nature Medicine

Cold exposure may be a potential therapy for diabetes by increasing brown adipose tissue (BAT) mass and activity. In a recent publication, DMRG shows that 10 d of cold acclimation (14–15 °C) increased peripheral insulin sensitivity by ~43% in eight type 2 diabetes subjects. Basal skeletal muscle GLUT4 translocation markedly increased, without effects on insulin signaling or AMP-activated protein kinase (AMPK) activation and only a minor increase in BAT glucose uptake.

The article was published in the influential journal Nature Medicine and immediately made it to the Dutch news headlines.